With hundreds of identified districts, Baltimore has been dubbed a "city of neighborhoods." Famous residents have included writers Edgar Allan Poe, Edith Hamilton, Frederick Douglass, and H. Mencken; jazz musician James "Eubie" Blake; singer Billie Holiday; actor and filmmaker John Waters; and baseball player Babe Ruth.
In the War of 1812, Francis Scott Key wrote The Star-Spangled Banner, which later became the American national anthem, in Baltimore.
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The Town of Baltimore, Jonestown, and Fells Point were incorporated as the City of Baltimore in 1796–1797.
The city remained a part of surrounding Baltimore County and continued to serve as its county seat from 1768–1851, after which it became an independent city.
Strikers clashed with the National Guard, leaving 10 dead and 25 wounded.
On February 7, 1904, the Great Baltimore Fire destroyed over 1,500 buildings in 30 hours, leaving more than 70 blocks of the downtown area burned to the ground.
Soon after the city created the world's first dental college, the Baltimore College of Dental Surgery, in 1840, and shared in the world's first telegraph line, between Baltimore and Washington DC in 1844.
Maryland, a slave state with abundant popular support for secession in some areas, remained part of the Union during the American Civil War, due in part to the Union's strategic occupation of the city in 1861.
As of 2016, the population of the Baltimore metropolitan area was estimated to be just under 2.8 million, making it the 21st largest metropolitan area in the country.
Baltimore is located about 40 miles northeast of Washington, D.
By 1820 its population had reached 60,000, and its economy had shifted from its base in tobacco plantations to sawmilling, shipbuilding, and textile production.